| 1995 |
Christopher
Page
Heart Sciences Centre, Harefield
|
Human endothelial
stimulation of allogenic T cells via a
CTLA-4 independent pathway |
|
| 1996 |
David Saitovitch
Nuffield Dept. Surgery, Oxford
|
Recipient
cells expressing single donor MHC locus
products can substitute for donor-specific
transfusion in the induction of transplantation
tolerance when pre-treatment is combined
with anti-Cd4 monoclonal antibody |
|
| 1997 |
Wilson Wong
Nuffield Dept. Surgery, Oxford
|
Pre-transplant
administration of a single donor class
1 major histocompatibility complex molecule
is sufficient for the indefinite survival
of fully allogeneic cardiac allografts |
|
| 1998 |
Louise Collins
& Lorna Shewring
Institute of Child Health, London
|
A non-viral
vector system for efficient gene transfer
to corneal endothelial cells via membrane
integrins |
|
| 1999 |
Sheng YUN
Institute of Child Health, London |
Suppression
of anti-porcine T-cell immune responses
by major histocompatibility complex class
II transactivator constructs lacking the
amino terminal domain |
|
| 2000 |
Gavin PETTIGREW
Dept. SurgeryCambridge |
Indirect
T cell allorecognition and allo-antibody
mediated rejection of MHC class I disparate
heart grafts |
|
| 2001 |
Nick JONES
Nuffield Dept. Surgery, Oxford |
CD40-CD40
ligand- independent activation of CD8
positive T cells can trigger allograft
rejection |
|
| 2002 |
Emma LOVEGROVE
Dept. Surgery, Cambridge |
Epitope
mapping of indirect T cell response to
allogenic class I MHC: sequences shared
by donor and recipient MHC may prime T
cells that provide help for alloantibody
production |
|
| 2003 |
Julian R
PRATT
Deptartment of Nephrology and Transplantation,
Guy's Hospital, London
|
Local synthesis
of complement component C3 regulates acute
renal transplant rejection |
|
| 2004 |
Nicola MONK
Deptartment of Nephrology and Transplantation,
Guy's Hospital, London.
|
Fc-dependent
depletion of activated T cells occurs
through CD40L-specific antibody rather
than costimulation blockade |
|
| 2005 |
Mahzuz Karim
Nuffield Dept of Surgery, Oxford
|
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process |
|
| 2006 |
Peng H Tan
Imperial College, London
|
Creation of tolerogenic
human dendritic cells via intracellular CTLA4: a novel
strategy with potential in clinical immunosuppression. |
|
| 2007 |
No award in 2007 |
|
|
| 2008 |
Kathryn Brown |
|
