| 1995 |
Christopher Page
Heart Sciences Centre, Harefield
|
Human endothelial stimulation of allogenic T cells via a CTLA-4 independent pathway |
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| 1996 |
David Saitovitch
Nuffield Dept. Surgery, Oxford
|
Recipient cells expressing single donor MHC locus products can substitute for donor-specific transfusion in the induction of transplantation tolerance when pre-treatment is combined with anti-Cd4 monoclonal antibody |
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| 1997 |
Wilson Wong
Nuffield Dept. Surgery, Oxford
|
Pre-transplant administration of a single donor class 1 major histocompatibility complex molecule is sufficient for the indefinite survival of fully allogeneic cardiac allografts |
|
| 1998 |
Louise Collins & Lorna Shewring
Institute of Child Health, London
|
A non-viral vector system for efficient gene transfer to corneal endothelial cells via membrane integrins |
|
| 1999 |
Sheng YUN
Institute of Child Health, London |
Suppression of anti-porcine T-cell immune responses by major histocompatibility complex class II transactivator constructs lacking the amino terminal domain |
|
| 2000 |
Gavin PETTIGREW
Dept. SurgeryCambridge |
Indirect T cell allorecognition and allo-antibody mediated rejection of MHC class I disparate heart grafts |
|
| 2001 |
Nick JONES
Nuffield Dept. Surgery, Oxford |
CD40-CD40 ligand- independent activation of CD8 positive T cells can trigger allograft rejection |
|
| 2002 |
Emma LOVEGROVE
Dept. Surgery, Cambridge |
Epitope mapping of indirect T cell response to allogenic class I MHC: sequences shared by donor and recipient MHC may prime T cells that provide help for alloantibody production |
|
| 2003 |
Julian R PRATT
Deptartment of Nephrology and Transplantation, Guy's Hospital, London
|
Local synthesis of complement component C3 regulates acute renal transplant rejection |
|
| 2004 |
Nicola MONK
Deptartment of Nephrology and Transplantation, Guy's Hospital, London.
|
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade |
|
| 2005 |
Mahzuz Karim
Nuffield Dept of Surgery, Oxford
|
Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process |
|
| 2006 |
Peng H Tan
Imperial College, London
|
Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. |
|
| 2007 |
No award in 2007 |
|
|
| 2008 |
Kathryn Brown |
|
|
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| 2009 |
Manuela Gaspar
|
Location and time-dependent control of rejection by regulatory T cells culminates in a failure to generate memory T cells.
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